RMM Grants Awarded

See where grants have been awarded across Minnesota.
Troy C. Lund, MD, PhD
Accelerating hematopoietic cell regeneration
Successful bone marrow transplant is the only way to cure a number of cancers, bone marrow failure syndromes, and other serious blood disease (like…
2018-2020
image of Joseph Lillegard, MD, PhD
Joseph Lillegard, MD, Phd
Gene therapy of hereditary Tyrosinemia Type I using in vivo lentiviral vectors
Hereditary Tyrosinemia Type 1 (HT1) is a genetic disorder that can lead to liver and kidney failure, and is fatal without treatment. There is no…
2018-2020
image of Daniel Garry, MD, PhD
Daniel Garry, MD, PhD
Bioengineering strategies for cardiovascular disease and regeneration
Cardiovascular disease is the most common cause of death in the United States, and many patients need heart transplants to survive. Currently,…
2018-2020
image of Terence Burns, MD, PhD
Terrence C. Burns, MD, PhD
Safety and mechanisms of senolytic therapy for central nervous system rejuvenation
The decline of memory and thinking processes seen in aging, neurodegenerative diseases (like Alzheimer’s disease), and exposure of the brain to…
2018-2020
image of Raghavendra Rao, MD
Raghavendra Rao, MD
Neuroprotection Using Human Extremely Low Gestational Age Neonate-Derived Umbilical Cord Blood Stem Cells in Neonatal Hemorrhagic Brain Injury
Each year in the United States, 12,000 extremely preterm infants (birth before 28 weeks of pregnancy) develop bleeding within the brain soon after…
2018-2020
image of Robert Tranquillo, PhD
Robert Tranquillo, PhD
Regenerative vein valve
Millions of U.S. citizens suffer from vein valve insufficiency, often resulting in chronic leg ulcers that cause pain, immobility, and a reduced…
2018-2020
image of Marija Cvetanovic, PhD
Marija Cvetanovic, PhD
Determining therapeutic potential of BDNF in delaying the onset and progression of Spinocerebellar ataxia type 1 (SCA1)
Spinocerebellar ataxia type 1 (SCA1) is a fatal neurodegenerative disease with no available therapies. This proposal will determine therapeutic…
2018-2020
image of Alexander Revzin, PhD
Alexander Revzin, PhD
Engineering microcapsules for stem cell cultivation and transplantation
The goal of this project is to develop microcapsules that could be used as cell carriers during differentiation of stem cells into pancreatic…
2018-2020
image of Ping Chen, PhD
Ping Chen, PhD
Regeneration of hypothalamic neuro-architecture using liver enzyme gene transfer as an approach to treat post-dieting body weight rebound
The major challenge in treating obesity is not just losing weight, but preventing weight from coming back. This proposal examines a new treatment…
2018-2019
image of Mohamad Bydon, MD
Mohamad Bydon, MD
CELLTOP: A Phase I Clinical Trial of Autologous Adipose Derived Mesenchymal Stem Cells in the Treatment of Paralysis due to Traumatic Spinal Cord Injury
This clinical trial investigates whether adipose-derived (fat tissue-derived) mesenchymal stem cells can be safely administered into the…
2018-2020
image of Nobuaki Kikyo, MD, PhD
Nobuaki J. Kikyo, MD, PhD
Circadian rhythm-based differentiation of iPS cells to cardiomyocytes
Many regenerative therapies are based on using a patient’s own cells to create induced pluripotent stem (iPS) cells that can then be differentiated…
2018-2020
image of Aaron Krych, MD
Aaron Krych, MD
The RECLAIM trial for focal cartilage repair
The goals of this project are to test the initial safety and feasibility of RECLAIM, a single stage cartilage repair technique using the patient’s…
2018-2020