Development of inducible immunodeficient swine
Grant Project Details:
Awardee:
Daniel Carlson, PhD
Timeframe:
2017-2018
Location:
Recombinetics | St Paul, MN
Amount:
$100,000
Status:
Complete
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Grant timeline: proposal, updates, reports
Grant Description
Immunodeficient swine have tremendous potential in basic and pre-clinical research; however, difficulties in propagation have impeded commercial availability. As a solution, we propose to build and test a conditional rescue cassette to pair with our RAG2/IL2Rg knockout swine to enable propagation. If successful, this project will lead to the first commercially available immunodeficient pig for regenerative medicine research and development.